The RCOE at the Mayo Clinic campus in Rochester, Minnesota is in the Department of Neurology which includes over 80 neurologists with permanent appointments to the medical staff. There are 12 neurology divisions, many (including the Behavioral Neurology Division) integrating subspecialty interests. The Department has several clinical and research laboratories. The Mayo Department of Neurology has a large clinical practice. This rich patient resource permits a broad and comprehensive range of clinical, educational, and research activities throughout the Department.

The Outreach and engagement staff at the Center provides support, information and guidance to those living with LBD and their families through in-person or virtual meetings, as well as workshops, programs, and events that focus on understanding the unique aspects of LBD, uncovering personal strengths, and promoting overall well-being. In addition, the Outreach and Engagement staff can connect people living with dementia and their care partners to LBD specific support groups, as well as dementia-friendly activities in the community at large, such as Memory cafes and arts based opportunities.