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Research

LBDA is pleased to offer the following articles on LBD-related research, written for the general public.

09/16/2013 - A new study examines for the first time in North America the incidence of Lewy body dementias and its distribution by age and sex in the general population.

9/26/2013 - New research into blood lipids in people with Parkinson’s disease may lead to blood tests that indicate which people with Parkinson’s are at risk for cognitive impairment and dementia.

05/01/2013 - A new study published in JAMA Neurology, analyzes how frequently new cases of parkinsonism were diagnosed in one geographic area of the U.S. and which proteinopathies were the underlying cause. 

01/03/2013 - While Lewy body disease can exist in a "pure" form — with little or no co-existing Alzheimer’s disease — at least half of individuals with Lewy body disease also have significant amounts of Alzheimer’s pathology. Research now reveals that a genetic variant that increases the risk of developing both early- and late-onset Alzheimer’s disease has been identified to also be a risk factor for Lewy body disorders.

01/03/2013 - Researchers at the University of Pennsylvania have discovered how Lewy body pathology spreads in the brain. Researchers injected a synthetic version of misfolded alpha-synuclein into the brain, which resulted in a cell to cell transmission of the rogue protein to the nerve cells near the injection site. Parkinson’s-like Lewy body pathology then developed in the brain. 

12/20/2012 - Capgras syndrome is a fairly common delusion is a recurrent, temporary belief that a familiar person, often a close family member or caregiver, or location has been replaced by an identical imposter. Read the latest research from the Pearl I. Barlow Center for Memory Evaluation and Treatment at the NYU Medical Center.

8/15/2012 - Two recent studies on the use of donepezil for dementia with Lewy bodies add to the strong case for cholinesterase inhibitor (ChEI) treatment in LBD.

7/9/2012 - REM sleep behavior disorder is a risk factor for disorders including Parkinson’s disease and Lewy body dementia that may precede those disorders by decades.

6/12/2012 - New research at Rush University Medical Center suggests earlier Parkinson’s diagnosis may be found by using colonoscopy.

6/12/2012 - At the American Academy of Neurology’s annual meeting in April, researchers from the Mayo Clinic reported on a small clinical trial which assessed the safety, tolerability and efficacy of armodafinil therapy for excessive sleepiness (hypersomnia) associated with dementia with Lewy bodies (DLB).